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CASE REPORT
Year : 2021  |  Volume : 12  |  Issue : 3  |  Page : 171-174

Adult-onset still's disease masquerading as hemophagocytic lymphohistiocytosis


1 Department of Medicine, Lady Hardinge Medical College and ABVIMS, RML Hospital, New Delhi, India
2 Department of Pathology, Lady Hardinge Medical College, New Delhi, India

Correspondence Address:
Dr. Aanchal Arora
F11 2nd Floor, Vikas Puri, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/injms.injms_34_21

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Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hematological condition caused by the overactivation of macrophages leading to widespread tissue destruction and organ dysfunction. The disease has a clinical overlap with adult-onset still's disease (AOSD) and hence poses a diagnostic challenge. We report the case of a 20-year-old female who presented with prolonged febrile illness, anemia, hepatosplenomegaly, and generalized lymphadenopathy. She was diagnosed with HLH and was readmitted 6 weeks later with recurrent fever, polyarthralgia, and pharyngitis. A diagnosis of AOSD with secondary HLH was made.


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