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Table of Contents
LETTER TO THE EDITOR
Year : 2022  |  Volume : 13  |  Issue : 2  |  Page : 134-135

White dots syndrome and pseudoxanthoma elasticum: An unusual association


Department of Ophthalmology, Military Hospital Mohammed V, Rabat, Morocco

Date of Submission10-Jan-2022
Date of Acceptance28-Jan-2022
Date of Web Publication21-Mar-2022

Correspondence Address:
Dr. Belfaiza Soukaina
Military Hospital Mohammed V, Rabat 0671266372
Morocco
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/injms.injms_5_22

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How to cite this article:
Soukaina B, Abdelaoui T, Jeddou I, Mouzari Y, Reda K, Abdelbar O. White dots syndrome and pseudoxanthoma elasticum: An unusual association. Indian J Med Spec 2022;13:134-5

How to cite this URL:
Soukaina B, Abdelaoui T, Jeddou I, Mouzari Y, Reda K, Abdelbar O. White dots syndrome and pseudoxanthoma elasticum: An unusual association. Indian J Med Spec [serial online] 2022 [cited 2022 Aug 15];13:134-5. Available from: http://www.ijms.in/text.asp?2022/13/2/134/340033



Dear Editor,

We report the case of a 38-year-old female patient, followed in dermatology for pseudoxanthoma elasticum, who was referred to ophthalmology as part of the evaluation of the extension of her disease. The ophthalmological examination revealed a visual acuity with correction estimated at 8/10 in both eyes and a normal biomicroscopic examination of the anterior segment. Funduscopy revealed hypo-pigmented white spots with angioid streaks at the posterior pole associated with an orange peel appearance in the temporo-macular region were found bilaterally [Figure 1]. Fluorescein retinal angiography showed hyperfluorescent punctiform lesions in the paramacular region and retinal periphery bilaterally [Figure 2].
Figure 1: Retinophotography of the posterior pole of the right eye (a) and the left eye (b) revealed hypo-pigmented white spots with angioid streaks at the posterior pole associated with an orange peel (arrow) appearance in the temporo-macular region were found bilaterally

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Figure 2: Fluorescein retinal angiography of the right eye (a) and the left eye (b) showed hyperfluorescent punctiform lesions in the paramacular region and retinal periphery

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Angioid streaks and orange peel appearance are the most common ocular manifestations of pseudoxanthoma elasticum,[1] whereas the hyperfluorescent white spot syndrome is an unusual manifestation that has been described only rarely in the literature.[2] The white spots, often discovered incidentally in the context of pseudoxanthoma elasticum, are explained histologically by peripheral rupture of Bruch's membrane.[2]

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

None.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Charbel Issa P, Finger RP, Götting C, Hendig D, Holz FG, Scholl HP. Centrifugal fundus abnormalities in pseudoxanthoma elasticum. Ophthalmology 2010;117:1406-14.  Back to cited text no. 1
    
2.
Trélohan A, Martin L, Milea D, Bonicel P, Ebran JM. Lésions rétiniennes dans le pseudoxanthome élastique: 51 cas. J Fr Ophtalmol 2011;34:456-67.  Back to cited text no. 2
    


    Figures

  [Figure 1], [Figure 2]



 

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