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ORIGINAL ARTICLE
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Clinical and laboratory profile of COVID-19 patients admitted at a tertiary care center in New Delhi and assessment of factors predicting disease severity


 Department of Medicine, ABVIMS, Dr RML Hospital, New Delhi, India

Correspondence Address:
Piyush Jain,
Department of Medicine, ABVIMS and RML Hospital, Delhi - 110001
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/injms.injms_158_20

Background: This study was conducted in nonintensive care unit COVID-19 patients admitted in a tertiary care center, to assess the clinical profile and find surrogate markers to predict the severity of COVID-19 at the time of admission. Methodology: It is a cross-sectional observational study. Clinical and laboratory data were compiled of patients admitted in COVID wards in a tertiary care center. Patients were stratified clinically according to the severity of COVID pneumonia. The admission clinical and laboratory parameters were compared between the severe and nonsevere COVID patients. Results: The study included 63 patients of which 46 were males, with a mean age of 47 years. Patients were classified into mild (32%), moderate (19%), and severe (49%) categories according to national guidelines. Fever (81%), cough (67%), and dyspnea (67%) were the most commonly observed symptoms. In comparative analysis, mean C-reactive protein (CRP), serum ferritin, and neutrophil–lymphocyte ratio (NLR) were significantly higher in severe COVID-19 patients and the admission PaCO2 significantly lower compared to nonsevere patients. Conclusion: The study shows that raised NLR, CRP, serum ferritin, and low PaCO2 levels at the time of admission are important predictors of disease severity.


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    -  Jain P
    -  Sinha N
    -  Prasad M K
    -  Padole V
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