Indian Journal of Medical Specialities

REVIEW ARTICLE
Year
: 2020  |  Volume : 11  |  Issue : 2  |  Page : 65--69

COVID 19 and immune phenomenon in children


Anu Maheshwari, Kaveri Pandit, Virendra Kumar, Deonath Mahto 
 Department of paediatrics, Kalawati Saran Children's Hospital and Lady Hardinge Medical College, New Delhi, India

Correspondence Address:
Dr. Anu Maheshwari
Department of Paediatrics, Kalawati Saran Children's Hospital and Lady Hardinge Medical College, Bangla Sahib Marg, New Delhi - 110 001
India

The novel coronavirus, named as severe acute respiratory syndrome (SARS)-CoV-2 has emerged as a global emergency. In December 2019, from a local outbreak in Wuhan, China, it has rapidly progressed to a global pandemic causing high morbidity and mortality exhausting all health-care facilities. COVID-19 is like any other respiratory virus but has more propensity to infect the lower parts of the respiratory system, namely bronchioles and alveoli. The innate and adaptive immune response helps the body to fight the virus. Atypical presentations such as Kawasaki disease, chilblain like lesions and other cutaneous manifestations, systemic inflammatory response syndrome-like illness (Toxic shock syndrome), Guillain–Barre syndrome, and other immune-related disorders have also been reported in various countries. Rapidly increasing cases worldwide have aroused global concerns regarding the need to understand the immunopathogenesis of the virus and possible explanations for various atypical manifestations occurring in children. This review is aimed at providing a complete understanding of the probable immune response in children and might predict future therapeutic target points.


How to cite this article:
Maheshwari A, Pandit K, Kumar V, Mahto D. COVID 19 and immune phenomenon in children.Indian J Med Spec 2020;11:65-69


How to cite this URL:
Maheshwari A, Pandit K, Kumar V, Mahto D. COVID 19 and immune phenomenon in children. Indian J Med Spec [serial online] 2020 [cited 2021 Jan 21 ];11:65-69
Available from: http://www.ijms.in/article.asp?issn=0976-2884;year=2020;volume=11;issue=2;spage=65;epage=69;aulast=Maheshwari;type=0